When running a Lotus Domino Server a wrong time can be very annoying, just imagine you have some agents not triggered at the expected (real) time. I have seen some Operating System time drift especially with Linux virtualized into VMware. I made some google searches and found that this problem seems to be quite common and there is lot of information on that issue.
I found a solution that works for me, which is to edit the boot options settings to add the following parameters:
acpi=off noapic nosmp nolapic clock=pit